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| Id: | 19344
| | Autor: | Rotberg, A. | | Título: | Some aspects of immunity in leprosy and their importance in epidemiology, pathogenesis and classification of forms of the disease: based on 1529 lepromin tested cases.
| | Fonte: | Rev. bras. Leprol;5(n.esp):45-97, 1937. ilus, tab, graf.
| | Resumo: | The author describes the technique employed in the preparation of lepromin, the types of reaction found, the criterion of reading, etc. He considers as positive reactions those with more than 5 mm diameter in the 30th day of reading. Reactions were studied in 1529 individuals, both lepers and healthy, with or no contact with leprosy; and the results are correlated with age, sex, race, nationality, degree of bacillary elimination, types of diseases, debility of the body through various diseases, speed of sedimentation of the red cells, lepra reaction, (present or prior to the test). Analyzing his results, together with the works of various authors, about lepromin, in endemic and non-endemic zones, and comparing the data with those of general pathology, in particular with tuberculosis, he arrives at the following conclusions: Epidemiology - Leprosy is a highly contagious but also highly immunizating disease. The bacillary leper in the propagator of the infection. However, close or prolonged contact with such bacillary casesis not necessary to acquire the infection. Hence, in endemic countries a large part of the population have been contaminated and immunized. Infection occurs naturally at younger ages, not because of special reciptivity in infancy, but rather because adults were already contaminated in their turn. (The author makes a distinction in childhood between "real" anergy and anergy of "non-infection"). A predisposition to leprosy exists, which is represented by an incapacity to react with the... (AU).
| | Descritores: | HANSENIASE
HANSENIASE/epidemiol
HANSENIASE/imunol
HANSENIASE/microbiol
TESTES CUTÂNEOS/clas
TESTES CUTÂNEOS/estatíst
| | Meio Eletrônico: | http://hansen.bvs.ilsl.br/textoc/revistas/Edicao%20Especial/1937/PDF/Ed.esp.a03.pdf - pt.
| | Localização: | BR191.1 |
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